급성 위장염 환아에서 bicarbonate gap의 임상적 의의 |
박규희, 정성관, 임형은, 유기환, 홍영숙, 이주원 |
1고려대학교 의과대학 소아과학교실 2고려대학교 의과대학 소아과학교실 3고려대학교 의과대학 소아과학교실 4고려대학교 의과대학 소아과학교실 5고려대학교 의과대학 소아과학교실 6고려대학교 의과대학 소아과학교실 |
Clinical Significance of Bicarbonate Gap in Pediatric Patients with Acute Gastroenteritis |
Kyu-Hee Park, Seong-Kwan Jung, Hyung-Eun Yim, Kee-Hwan Yoo, Young-Sook Hong, Joo-Won Lee |
1Department of Pediatrics, College of Medicine 2Department of Pediatrics, College of Medicine 3Department of Pediatrics, College of Medicine 4Department of Pediatrics, College of Medicine 5Department of Pediatrics, College of Medicine 6Department of Pediatrics, College of Medicine |
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ABSTRACT |
PURPOSE: The purpose of this study was to determine the clinical value of bicarbonate gap (BG) in acute gastroenteritis by comparison of clinical manifestations and laboratory findings. METHODS: We retrospectively analyzed 135 patients who had acute gastroenteritis. We classified them into two groups: BG< or =-5 (group A), BG>-5 (group B). We made a comparative study for clinical manifestations, serum electrolyte, albumin, protein, blood urea nitrogen (BUN), creatinine, anion gap (AG), delta anion gap (deltaAG) and delta bicarbonate (deltaHCO3-) between the two groups. RESULTS: The duration of hospitalization and diarrhea was significantly longer in group A than group B. In laboratory findings, serum sodium, serum total CO2, total protein, AGcorrected and deltaAG were lower in group A than group B. deltaHCO3- and chloride were higher in group A than group B. CONCLUSION: BG may be a sensitive predictor enough to access the severity of acute gastroenteritis. |
Key words:
Acute gastroenteritis | Metabolic acidosis | Delta anion gap | Delta bicarbonate |
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