A Case about Cyclosporine Treatment of Kimura's Disease Associated with Steroid Dependant Nephrotic Syndrome

Do, Young-Sun; Kim, Hak-Yong; NamGoong, Mee-Kyung

doi:2009.13.2.271

J Korean Soc Pediatr Nephrol > Volume 13(2); 2009 > Article

J Korean Soc Pediatr Nephrol 2009;13(2): 271-277. doi: https://doi.org/10.3339/jkspn.2009.13.2.271

스테로이드 의존형 신증후군과 동반된 기무라병에서 cyclosporine 치료 경험

도영선, 김학용, 남궁미경

¹연세대학교 원주의과대학 소아청소년과
²연세대학교 원주의과대학 소아청소년과
³연세대학교 원주의과대학 소아청소년과

A Case about Cyclosporine Treatment of Kimura's Disease Associated with Steroid Dependant Nephrotic Syndrome

Young-Sun Do, Hak-Yong Kim, Mee-Kyung NamGoong

¹Department of Pediatrics and Adolescent Medicine, Wonju Christian Hospital Yonsei University Wonju College of Medicine
²Department of Pediatrics and Adolescent Medicine, Wonju Christian Hospital Yonsei University Wonju College of Medicine
³Department of Pediatrics and Adolescent Medicine, Wonju Christian Hospital Yonsei University Wonju College of Medicine

ABSTRACT

Kimura's disease is a chronic inflammatory disorder of unknown etiology. A 14 year old boy suffering from steroid dependant nephrotic syndrome, was presented with relapsing painless subcutaneous masses on the left buccal area. Blood analysis showed increased IgE and eosinophilia. During 4 years follow up, he was been treated by low dose steroid and short term cyclosporine. Consequently, frequent relapses of subcutaneous masses and nephrotic syndrome has been relieved. Cyclosporine treatment combined with steroid may be useful for preventing frequent relapse of Kimura's disease.

Key words: Kimura's disease | Steroid dependant nephrotic syndrome | Cyclosporine