Child Kidney Dis > Volume 24(1); 2020 > Article |
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No. | Age (Years) | Sex | Stage | Number of glomeruli | IgA | IgG | IgM | C3 | C4 | C1q | PLA2R | Additional Finding* | EM** | Treatment (month) | Outcome† (month) | Seroconversion‡ |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 9 | M | I–III | 61 | - | ++ | - | - | - | - | - | Mesangial expansion with hypercellularity Cannot exclude CsA toxicity | Subepithelial and some minute subendothelial, intramembranous, mesangial EDD | Cyclosporine A (8) and alphainterferon (15) | UA normal (3) | After 4 years |
2 | 11 | M | II–III | 21 | - | ++ | + | + | - | - | - | FSGS in 1 glomerulus | Subepithelial and no mesangial EDD | Cyclosporine A (3) | UA normal (22) | After 5 years |
2 | 13 | M | II–III | 14 | - | + | + | + | - | - | - | - | ACE inhibitor and glucocorticoid | UA normal (4) | ||
3 | 9 | F | III | 28 | - | ++ | ++ | ++ | - | + | - | - | Cyclosporine A (13) | UA normal (29) | ||
3 | 10 | F | II | 36 | - | ++ | + | + | - | - | - | - | UA normal (1) | |||
4 | 13 | M | II | 15 | - | ++ | - | - | - | + | + | - | ACE inhibitor and glucocorticoid | |||
5 | 7 | M | II–III | 62 | - | ++ | - | + | - | + | - | Subepithelial EDD and mesangial slight widening with some EDD | ACE inhibitor and glucocorticoid | |||
6 | 5 | M | II–III | 139 | - | ++ | - | - | + | - | - | - | Cyclosporine A (23) and alphainterferon (4–6) | UA protein free (13) | After 3 years | |
7 | 11 | F | I | 54 | + | ++ | + | + | + | - | - | - | ACE inhibitor and glucocorticoid | UA normal (22) | After 1 year | |
8 | 10 | M | II | 31 | - | ++ | + | + | - | + | - | Spotty IgM in mesangium | - | Alpha-interferon (3) | UA protein free (6), relapse (13) and UA normal (24) | After 3 years |
9 | 15 | M | II | 23 | - | ++ | - | - | - | + | - | Minimal segmental mesangial expansion with increased cellularity in 3 glomeruli | - | ACE inhibitor and glucocorticoid | UA normal (6) | After 2 months |
10 | 3 | M | II | 39 | - | +++ | - | ++ | - | - | + | - | ACE inhibitor and glucocorticoid | UA protein free (1) follow-up biopsy showed remission (108) | After 3 years | |
10 | 8 | M | II–III | 17-19 | - | + | - | - | - | - | + | - | ACE inhibitor and glucocorticoid |
Sung-Eun Choi
https://orcid.org/0000-0002-6955-658X
Keum Hwa Lee
https://orcid.org/0000-0002-1511-9587
Jae Il Shin
https://orcid.org/0000-0003-2326-1820
Hyeon Joo Jeong
https://orcid.org/0000-0002-9695-1227
Beom Jin Lim
https://orcid.org/0000-0003-2856-0133