Prevalence of Vesicoureteral Reflux According to the Timing of Voiding Cystourethrography in Infantile Urinary Tract Infection

Oh, Yoon-Su; Choi, Min-Jeong; Park, Se-Jin; Lee, Jae-Seung; Shin, Jae-Il; Kim, Kee-Hyuck

doi:2011.15.2.163

J Korean Soc Pediatr Nephrol > Volume 15(2); 2011 > Article

J Korean Soc Pediatr Nephrol 2011;15(2): 163-171. doi: https://doi.org/10.3339/jkspn.2011.15.2.163

영아 요로감염에서 배뇨방광요도조영술 시기에 따른 방광요관역류의 발생 빈도: 두 기관 비교 연구

오윤수, 최민정, 박세진, 이재승, 신재일, 김기혁

¹연세대학교 의과대학 소아과학교실
²연세대학교 의과대학 소아과학교실
³아주대학교 의과대학 소아과학교실
⁴연세대학교 의과대학 소아과학교실
⁵연세대학교 의과대학 소아과학교실
⁶국민건강보험공단 일산병원 소아청소년과

Prevalence of Vesicoureteral Reflux According to the Timing of Voiding Cystourethrography in Infantile Urinary Tract Infection

Yoon-Su Oh, Min-Jeong Choi, Se-Jin Park, Jae-Seung Lee, Jae-Il Shin, Kee-Hyuck Kim

¹Department of Pediatrics, Yonsei University College of Medicine
²Department of Pediatrics, Yonsei University College of Medicine
³Department of Pediatrics, Ajou University School of Medicine
⁴Department of Pediatrics, Yonsei University College of Medicine
⁵Department of Pediatrics, Yonsei University College of Medicine
⁶Department of Pediatrics, National Health Insurance Corporation Ilsan Hospital

Received: March 24, 2011; Accepted: September 16, 2011.

ABSTRACT

Purpose : To evaluate the prevalence of vesicoureteral reflux (VUR) according to the timing of voiding cystourethrography (VCUG) in infantile urinary tract infection (UTI).
Methods : The data of 134 infants (1-12 months) with renal cortical defect in $^{99m}Tc$-2, 3-dimercaptosuccinic acid ($^{99m}Tc$-DMSA) scan with a diagnosis of UTI in two hospitals from 2000 to 2010 were retrospectively analyzed. The VCUG was performed after 2 weeks from the diagnosis of UTI in Group I (n=68), and the VCUG was performed within 2 weeks from the diagnosis of UTI in Group II (n=66).
Results : There were no significant differences between the two groups in the duration of fever, white blood cell count, C-reactive protein levels, and abnormalities in ultrasonography (P>0.05). There was no significant difference between the two groups in the prevelence of VUR, bilateral VUR, and severe VUR. VCUG-induced UTI was detected 16 (23.5%) of patients in whom the procedure was performed 2 weeks after the diagnosis, and none of VCUG-induced UTI occurred in those in whom the procedure was performed 2 weeks within the diagnosis.
Conclusion : We conclude that the prevalence of VUR according to the timing of VCUG did not differ between the two groups in infantile UTI with renal cortical defect in DMSA scan. We also found that performing VCUG with antibiotics can decrease risk of VCUG-induced UTI.

Key words: Urinary tract infection | $^{99m}Tc$-DMSA scan | Voiding cystourethrography | Vesicoureteral reflux