A Case of Nephrotic Syndrome with Swine-origin H1N1 Influenza Virus

Kim, Sae-Yoon; Kim, Myoung-Uk; Lee, Sang-Su; Park, Yong-Hoon

doi:2010.14.2.218

J Korean Soc Pediatr Nephrol > Volume 14(2); 2010 > Article

J Korean Soc Pediatr Nephrol 2010;14(2): 218-222. doi: https://doi.org/10.3339/jkspn.2010.14.2.218

H1N1 인플루엔자 바이러스 감염과 동반되어 발생한 신증후군 1례

김세윤, 김명욱, 이상수, 박용훈

¹영남대학교 의과대학 소아청소년과
²영남대학교 의과대학 소아청소년과
³영남대학교 의과대학 소아청소년과
⁴영남대학교 의과대학 소아청소년과

A Case of Nephrotic Syndrome with Swine-origin H1N1 Influenza Virus

Sae-Yoon Kim, Myoung-Uk Kim, Sang-Su Lee, Yong-Hoon Park

¹Department of Pediatrics, Yeungnam University College of Medicine
²Department of Pediatrics, Yeungnam University College of Medicine
³Department of Pediatrics, Yeungnam University College of Medicine
⁴Department of Pediatrics, Yeungnam University College of Medicine

Received: March 28, 2010; Revised: May 7, 2010. Accepted: August 27, 2010.

ABSTRACT

Nephrotic syndrome is a clinical syndrome characterized by heavy proteinuria, hypoalbuminemia, edema and hyperlipidemia. Causes of idiopathic nephrotic syndrome include minimal change nephrotic syndrome (MCNS), focal segmental glomerulosclerosis (FSGS) and mesangial proliferation. Other causes of nephrotic syndrome are rare genetic disorders and secondary diseases associated with drugs, infections, or neoplasia. Since February 2009, a swine-origin H1N1 influenza virus (S-OIV) from Mexico has been spread among humans in unexpected rapidity. S-OIV is markedly different from seasonal influenza, in that many of those affected are previously healthy young people. While pulmonary complications of S-OIV infection have been frequently documented, renal complications have not been as widely recognized. We report a case of 4 year-old boy who had developed nephrotic syndrome after S-OIV infection with good response after steroid treatment.

Key words: H1N1 influenza | Nephrotic syndrome | Oseltamivir