Clinical Parameters Predicting Responsiveness to Treatment in Enuresis Patients

Lee, Kang-Gyoon; Lee, Hyun-Jung; Lim, Yun-Ju; Kwon, Duck-Geun; Kim, Eun-Jin; Pai, Ki-Soo

doi:2007.11.2.272

J Korean Soc Pediatr Nephrol > Volume 11(2); 2007 > Article

J Korean Soc Pediatr Nephrol 2007;11(2): 272-279. doi: https://doi.org/10.3339/jkspn.2007.11.2.272

야뇨증 치료반응 예측에 관계하는 평가지표

이강균, 이현정, 임윤주, 권덕근, 김은진, 배기수

¹아주대학교 의과대학 소아청소년과학교실
²아주대학교 의과대학 소아청소년과학교실
³아주대학교 의과대학 소아청소년과학교실
⁴아주대학교 의과대학 소아청소년과학교실
⁵아주대학교 의과대학 소아청소년과학교실
⁶아주대학교 의과대학 소아청소년과학교실

Clinical Parameters Predicting Responsiveness to Treatment in Enuresis Patients

Kang-Gyoon Lee, Hyun-Jung Lee, Yun-Ju Lim, Duck-Geun Kwon, Eun-Jin Kim, Ki-Soo Pai

¹Department. of Pediatrics and Adolescent Medicine Ajou University School of Medicine
²Department. of Pediatrics and Adolescent Medicine Ajou University School of Medicine
³Department. of Pediatrics and Adolescent Medicine Ajou University School of Medicine
⁴Department. of Pediatrics and Adolescent Medicine Ajou University School of Medicine
⁵Department. of Pediatrics and Adolescent Medicine Ajou University School of Medicine
⁶Department. of Pediatrics and Adolescent Medicine Ajou University School of Medicine

ABSTRACT

Purpose : We tried to find out the clinical parameters which predict the outcome of treatment in children with enuresis.
Methods : Enuresis patients who visited our hospital during 2003-2007 were included. Parameters such as age, gender, height, weight, minimal voided volume, maximal voided volume, maximum functional bladder capacity, frequency of voiding, urine S,G. before and after sleep were measured and an enuresis diary was also recorded. The reduction in wetting frequencies were classified into three groups; none(<50%), partial(50-90%) and complete(90%) response groups. We also compared the 'initial responders' who showed improvement(${ge}50%$) during the 2 weeks of evaluation and behavioral therapy to the 'initial non-responders'.
Results : Parameters mentioned above showed no significant relation to the treatment out-come. The response rate during the 2 weeks of the evaluation period was 32%(49/151) [complete in 1.3% (2/151), partial in 29.6% (47/151)]. Two-months' treatment responses were complete in 14(40%), partial in 19(54.3%) and none in 2(5.9%) responders(n=35), while they were 10(13.5%), 46(62.2%) and 18(24.3%), respectively in the non-responders(n=73) (P<0.05).
Conclusion : We suggest that initial 'responsiveness' can be used as a predictor for good treatment outcome in patients with enuresis.

Key words: Enuresis frequency | Initial responders | Treatment response | Urine specific gravity | Behavioral therapy