A Case of Henoch-Schonlein Purpura with Hemorrhagic Bullae in a Child

Oh, Yeon-Mi; Jung, Mi-Rim; Choi, Hye-Jeong; Cha, Hee-Jeong; Jeong, Jin-Young

J Korean Soc Pediatr Nephrol > Volume 10(1); 2006 > Article

J Korean Soc Pediatr Nephrol 2006;10(1): 40-44.

소아에서 출혈성 수포를 동반한 Henoch-Schönlein 자반병 1례

오연미, 정미림, 최혜정, 차희정, 정진영

¹울산대학교 의과대학 울산대학교병원 소아과
²울산대학교 의과대학 울산대학교병원 소아과
³울산대학교 의과대학 울산대학교병원 병리과
⁴울산대학교 의과대학 울산대학교병원 병리과
⁵울산대학교 의과대학 울산대학교병원 소아과

A Case of Henoch-Schonlein Purpura with Hemorrhagic Bullae in a Child

Yeon-Mi Oh, Mi-Rim Jung, Hye-Jeong Choi, Hee-Jeong Cha, Jin-Young Jeong

¹Department of Pediatrics, Ulsan University College of Medicine
²Department of Pediatrics, Ulsan University College of Medicine
³Department of Pathology, Ulsan University College of Medicine
⁴Department of Pathology, Ulsan University College of Medicine
⁵Department of Pediatrics, Ulsan University College of Medicine

ABSTRACT

Henoch-Schonlein purpura(HSP) is a systemic small vessel vasculitis characterized by cutaneous purpura, arthritis, abdominal pain and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. In this case report, the patient presented with arthralgia and abdominal pain and had hemorrhagic bullae as a prominent manifestation of the disease. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis of dermal vessels and prominent IgA and fibrinogen deposits on capillary walls by direct immunofluorescence. We confirmed the diagnosis of HSP and observed improvement of clinical symptoms and signs within a few days after corticosteroid treatment. We therefore report a case with a review of the literature.

Key words: Henoch-Schonlein purpura | Hemorrhagic bullae | Leukocytoclastic vasculitis | IgA | Fibrinogen