Acute Leukoencephalopathy During Cyclosporin A Therapy in a Pediatric Patient with Nephrotic Syndrome

Jung, Suk-Won; Rhee, Kyung-Hwa; Kwon, Young-Se; Kim, Soon-Ki; Son, Byong-Kwan; Lee, Ji-Eun

J Korean Soc Pediatr Nephrol > Volume 9(1); 2005 > Article

J Korean Soc Pediatr Nephrol 2005;9(1): 91-96.

신 증후군 환아에서 Cyclosporin A 치료 중 발생한 급성 백색질 뇌증 1례

정석원, 이경화, 권영세, 김순기, 손병관, 이지은

¹인하대학교 의과대학 소아과학교실
²인하대학교 의과대학 소아과학교실
³인하대학교 의과대학 소아과학교실
⁴인하대학교 의과대학 소아과학교실
⁵인하대학교 의과대학 소아과학교실
⁶인하대학교 의과대학 소아과학교실

Acute Leukoencephalopathy During Cyclosporin A Therapy in a Pediatric Patient with Nephrotic Syndrome

Suk-Won Jung, Kyung-Hwa Rhee, Young-Se Kwon, Soon-Ki Kim, Byong-Kwan Son, Ji-Eun Lee

¹Department of Pediatrics, College of Medicine, inha University
²Department of Pediatrics, College of Medicine, inha University
³Department of Pediatrics, College of Medicine, inha University
⁴Department of Pediatrics, College of Medicine, inha University
⁵Department of Pediatrics, College of Medicine, inha University
⁶Department of Pediatrics, College of Medicine, inha University

ABSTRACT

Cyclosporin A-induced central neurotoxicity has been rarely reported in patients with nephrotic syndrome. We report a pediatric patient who developed acute leukoencephalopathy diagnosed by MRI during CsA therapy for nephrotic syndrome.

Key words: Acute leukoencephalopathy | Cyclosporin A | Nephrotic syndrome