A Case of Hemolytic Uremic Syndrome in a Child with Ischemic Colitis

Kim, Yang-Hyun; Ahn, Sun-Young; Park, Ji-Min; Lee, Jae-Seung

J Korean Soc Pediatr Nephrol > Volume 8(1); 2004 > Article

J Korean Soc Pediatr Nephrol 2004;8(1): 86-90.

허혈성 대장염에 동반된 용혈성 요독 증후군 1례

김양현, 안선영, 박지민, 이재승

¹연세대학교 의과대학 소아과학교실, 신장질환연구소
²연세대학교 의과대학 소아과학교실, 신장질환연구소
³연세대학교 의과대학 소아과학교실, 신장질환연구소
⁴연세대학교 의과대학 소아과학교실, 신장질환연구소

A Case of Hemolytic Uremic Syndrome in a Child with Ischemic Colitis

Yang-Hyun Kim, Sun-Young Ahn, Ji-Min Park, Jae-Seung Lee

¹Department of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
²Department of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
³Department of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
⁴Department of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine

ABSTRACT

Hemolytic uremic syndrome(HUS) is characterized by acute renal failure, microangiopathic hemolytic anemia, and thrombocytopenia and the most common pathogen is Escherichia coli (E. coli) O157:H7. Ischemic colitis, which rarely occurs in children, is due to the reduced local blood flow to the intestine, tissue necrosis and secondary bacterial infection. We describe a patient who was admitted with abdominal pain, vomiting and hematochezia, and diagnosed as ischemic colitis by barium enema. This patient showed hemolytic anemia, thrombocytopenia and progressive renal failure and was subsequently diagnosed as hemolytic uremic syndrome. After hemodialysis, the patient showed improvement of symptoms and resolution of renal failure and ischemic colitis.

Key words: Hemolytic uremic syndrome | Ischemic colitis