소아 악성 고열증과 동반되어 발생한 횡문근융해증 1례 |
이범희, 이진숙, 조희연, 강주형, 강희경, 정해일, 최용, 하일수 |
1서울대학교 의과대학 소아과학교실 2서울대학교 의과대학 소아과학교실 3서울대학교 의과대학 소아과학교실 4서울대학교 의과대학 소아과학교실 5서울대학교 의과대학 소아과학교실 6서울대학교 의과대학 소아과학교실 7서울대학교 의과대학 소아과학교실 8서울대학교 의과대학 소아과학교실 |
A Case of Childhood Malignant Hyperthermia Complicated by Rhabdomyolysis |
Bum-Hee Lee, Jin-Sook Lee, Hee-Yeon Cho, Ju-Hyung Kang, Hee-Gyung Kang, Hae-Il Cheong, Yong Choi, Il-Soo Ha |
1Department of Pediatrics, Seoul National University College of Medicine 2Department of Pediatrics, Seoul National University College of Medicine 3Department of Pediatrics, Seoul National University College of Medicine 4Department of Pediatrics, Seoul National University College of Medicine 5Department of Pediatrics, Seoul National University College of Medicine 6Department of Pediatrics, Seoul National University College of Medicine 7Department of Pediatrics, Seoul National University College of Medicine 8Department of Pediatrics, Seoul National University College of Medicine |
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ABSTRACT |
Mortality and morbidity of malignant hyperthermia has decreased markedly by the avoidance of succinylcholine, and the earlier detection and introduction of dantrolene. We report a fourteen-year-old boy who developed malignant hyperthermia during general anesthesia. He showed the earlier clinical signs, such as elevation of end-tidal CO2, tachycardia, and hypertension. After prompt administration of dantrolene, operation was continued with profopol and midazolam. Rhabdomyolysis and myoglobinuria followed, and were managed by hydration and alkalinization of urine. Azotemia did not occur, and he was discharged without any sequelae on the 10th postoperative day. |
Key words:
Dantrolene | General anaesthesia | Rhabdomyolysis | Malignant hyperthermia |
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