A Case of Henoch-Schonlein Nephritis Mimicking Acute Poststreptococcal Glomerulonephritis in Histology

Chung, Hyo-Seok; Lee, Hyun-Kyung; Kim, Yong-Jin; Park, Yong-Hoon

J Korean Soc Pediatr Nephrol > Volume 7(1); 2003 > Article

J Korean Soc Pediatr Nephrol 2003;7(1): 73-76.

급성 사구체신염의 조직소견을 보인 Henoch-Schönlein 자반증 신염 1례

정효석, 이현경, 김용진, 박용훈

¹영남대학교 의과대학 소아과학교실
²영남대학교 의과대학 소아과학교실
³영남대학교 의과대학 병리학교실
⁴영남대학교 의과대학 소아과학교실

A Case of Henoch-Schonlein Nephritis Mimicking Acute Poststreptococcal Glomerulonephritis in Histology

Hyo-Seok Chung, Hyun-Kyung Lee, Yong-Jin Kim, Yong-Hoon Park

¹Departments of Pediatrics, Yeungnam University, College of Medicine
²Departments of Pediatrics, Yeungnam University, College of Medicine
³Departments of Pathology, Yeungnam University, College of Medicine
⁴Departments of Pediatrics, Yeungnam University, College of Medicine

ABSTRACT

A girl aged 21 months with Henoch-Schonlein purpura(HSP) developed heavy proteinuria with hematuria 8 days after the appearance of purpuric rash, swelling and tenderness of both ankle joints. Her clinical and laboratory features demonstrated nephrotic and nephritic syndrome. The percutaneous renal biopsy revealed diffuse mesangial proliferative glomerulonephritis. Unlike usual HSP nephritis, immunoglobulin A deposition was not detected in the mesangium or the capillary of the glomeruli. Instead, numerous subepithelial electron-dense deposits("humps") mimicking acute poststreptococcal glomerulonephritis were found.

Key words: Henoch-Schonlein nephritis