Two Cases of Hemolytic Uremic Syndrome Associated with Pneumococcal Infection

Jo, Seung-Heui; Park, Kyung-Mi; Ha, Il-Soo; Cheong, Hae-Il; Choi, Yong

J Korean Soc Pediatr Nephrol > Volume 3(2); 1999 > Article

J Korean Soc Pediatr Nephrol 1999;3(2): 227-231.

폐렴구균 감염에 동반된 비전형적 용혈성 요독 증후군 2례

조승희, 박경미, 하일수, 정해일, 최용

¹서울대학교 의과대학 소아과학교실
²서울대학교 의과대학 소아과학교실
³서울대학교 의과대학 소아과학교실
⁴서울대학교 의과대학 소아과학교실
⁵서울대학교 의과대학 소아과학교실

Two Cases of Hemolytic Uremic Syndrome Associated with Pneumococcal Infection

Seung-Heui Jo, Kyung-Mi Park, Il-Soo Ha, Hae-Il (NULL) Cheong, Yong Choi

¹Department of Pediatrics, Seoul National University College of Medicine
²Department of Pediatrics, Seoul National University College of Medicine
³Department of Pediatrics, Seoul National University College of Medicine
⁴Department of Pediatrics, Seoul National University College of Medicine
⁵Department of Pediatrics, Seoul National University College of Medicine

ABSTRACT

Hemolytic uremic syndrome is a clinical syndrome with various etiology and pathogenesis. And pneumococcal neuraminidase has been known to play a pathogenetic role in some cases with this syndrome. We experienced two children with hemolytic uremic syndrome complicated by pneumococcal infection. One was 21-month-old girl with pneumococcal pneumonia, and the other was 7-month-old girl with pneumococcal meningitis and sepsis. Both of them showed typical clinical manifestations of hemolytic uremic syndrome with prolonged anuria during the course of pneumococcal infection. The renal functions of both cases did not recovered after resolution of acute hemolytic episode and chronic renal failure developed.

Key words: Hemolytic uremic syndrome | Pneumococcal infection