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Journal of the Korean Society of Pediatric Nephrology 1997;1(1): 79-81.
급성 신부전증을 동반한 미세변화 신증후군 1례
박수준, 노광식, 이구현, 김병길, 정현주
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 소아과학교실
3연세대학교 의과대학 소아과학교실
4연세대학교 의과대학 소아과학교실
5연세대학교 의과대학 병리학교실
Minimal Change Nephrotic Syndrome Presented with Acute Renal Failure in a Child
Soo-Jun Park, Kwang-Sik Rho, Gu-Hyun Lee, Pyung-Kil Kim, Hyeon-Joo Jeong
1Departments of Pediatrics, Institute of Kidney Disease Yonsei University, College of Medicine
2Departments of Pediatrics, Institute of Kidney Disease Yonsei University, College of Medicine
3Departments of Pediatrics, Institute of Kidney Disease Yonsei University, College of Medicine
4Departments of Pediatrics, Institute of Kidney Disease Yonsei University, College of Medicine
5Departments of Pathology, Institute of Kidney Disease Yonsei University, College of Medicine
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ABSTRACT
Minimal change nephrotic syndrome is characterized by proteinuria, hypoproteinemia, edema, and hyperlipidemia. Children with onset of nephrotic syndrome between the age of 1 and 8 year are likely to have steroid response to minimal chage disease, but we experienced one case of minimal change disease which failed to respond to steroid therapy at beginning and subsequently developed acute renal failure. It was seen in a 5 year-old male child that presented with edema and gross hematuria. Peritoneal dialysis was performed for acute renal failure for 11 days. Patient was completely recorvered from acute renal failure and renal biopsy was done at 27th day after onset of disease which revealed typical picture of minimal change disease complicated by acute tubular necrosis. We beleive this case is very unusual and it may be the first case in the literature in terms of pediatric cases.
Key words: Minimal change nephrotic syndrome | Acute renal failure Acute tubular necrosis
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