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Journal of the Korean Society of Pediatric Nephrology 1997;1(1): 24-30.
발열성 요로감염 환아의 $^{99m}Tc-DMSA$ 신주사에서 절대적 신섭취율과 상대적 신섭취율의 진단적 가치에 대한 비교연구
김희연, 배상영, 황수자, 박은애, 김호성, 서정완, 이승주
1이화여자대학교 의과대학 소아과학교실
2이화여자대학교 의과대학 소아과학교실
3이화여자대학교 의과대학 소아과학교실
4이화여자대학교 의과대학 소아과학교실
5이화여자대학교 의과대학 소아과학교실
6이화여자대학교 의과대학 소아과학교실
7이화여자대학교 의과대학 소아과학교실
Comparison of Diagnostic Value between the Absolute and Relative Uptake Rate on $^{99m}Tc-DMSA$ Renal Scan of Children with Febrile Urinary Tract Infection
Hee-Yeon Kim, Sang-Young Bae, Su-Ja Whang, Eun-Ae Park, Ho-Sung Kim, Jung-Wan Seo, Sung-Joo Lee
1Department of Pediatrics, Ewha Womans University, College of Medicine
2Department of Pediatrics, Ewha Womans University, College of Medicine
3Department of Pediatrics, Ewha Womans University, College of Medicine
4Department of Pediatrics, Ewha Womans University, College of Medicine
5Department of Pediatrics, Ewha Womans University, College of Medicine
6Department of Pediatrics, Ewha Womans University, College of Medicine
7Department of Pediatrics, Ewha Womans University, College of Medicine
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ABSTRACT
Purpose: To evaluate the diagnositc value of the absolute and relative renal uptake rates on $^{99m}Tc-DMSA$ renal scan of children with febrile UTI.
Method : The absolute and relative renal uptake rates of $^{99m}Tc-DMSA$ were checked in 68 children with febrile urinary tract infection (35 with unilateral focal defect; 13 with bilateral focal defect; and 20 with diffuse bilateral defect) and 49 children with afebrile UTI and normal $^{99m}Tc-DMSA$ renal scan as control.
Results : The renal absolute uptake rate in the control group were $21.8{pm}3.9%(right),;22.2{pm}3.9%(left),;and;44.2{pm}7.8%(total)$. The absolute uptake rate gradually increased until the age 12 months and then was stationary. In febrile UTI with unilateral focal defect on the $^{99m}Tc-DMSA$ renal scan, both relative and absolute uptake rates were similarly diagnostic ($41.2{pm}9.7%,;16.5{pm}5.4%$ vs $50.0{pm}2.6%,;22.0{pm}3.9%$, p<0.01). In acute pyelonephritis with bilateral focal defect on the $^{99m}Tc-DMSA$ renal scan, the absolute uptake rate was significantly more diagnostic than the relative uptake rate[$17.3{pm}5.3%$ (right), $17.4{pm}5.3%;(left),;vs;21.8{pm}3.9%,;(right);22.2{pm}3.9%$, (left)% p<0.01]. In febrile UTI with bilateral diffuse defects on the $^{99m}Tc-DMSA$ renal scan, the absolute uptake rate was significantly diagnostic than the relative uptake rate [$18.1{pm}3.9%;(right),;18.4{pm}3.8%;(left),;vs;21.8{pm}3.9%,;(right);22.2{pm}3.9%$(left), p<0.01].
Conclusion : In the $^{99m}Tc-DMSA$ renal scan, the absolute uptake rate was more useful than the relative uptake rate to evaluate bilateral acute pyelonephritis.
Key words: The absolute & relative uptake rates | $^{99m}Tc-DMSA$ renal scan | UTI
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