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Journal of the Korean Society of Pediatric Nephrology 2014;18(2): 132-136. doi: https://doi.org/10.3339/jkspn.2014.18.2.132
Various Renal Manifestations in Children with Tuberous Sclerosis Complex
Ja Hyun Lim1, Moon Sung Park1, Ki Soo Pai1, Sung Hwan Kim1, Jae Il Shin2, Se Jin Park3
1Department of Pediatrics, Ajou University School of Medicine, Ajou University Hospital, Suwon, Korea
2Department of Pediatrics, Yonsei University College of Medicine, Severance Children’s Hospital, Seoul, Korea
3Department of Pediatrics, Ajou University School of Medicine, Daewoo General Hospital, Geoje, Korea
Corresponding Author: Se Jin Park ,Tel: +82-55-680-8148, Fax: +82-55-680-8412, Email: fli018@hanmail.net
Received: September 25, 2014;  Accepted: October 20, 2014.
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ABSTRACT
Tuberous sclerosis complex (TSC) is a genetic disorder that affects multiple organ systems and causes tumors. It is important that physicians are aware of the manifestations of TSC, and that they follow the recommendations for screening and evaluation. Several types of renal abnormalities may develop in individuals with TSC. Individuals with TSC may require ongoing treatment that can be adapted for each arising manifestation of renal disease. Herein, we report 4 patients with TSC who presented with a range of different renal manifestations, including angiomyolipoma, renal cell carcinoma, renal infarction, renal cyst, and nephrolithiasis.
Key words: Tuberous sclerosis | Angiomyolipoma | Renal cell carcinoma | Renal infarction | Renal cyst | Nephrolithiasis
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