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Journal of the Korean Society of Pediatric Nephrology 2014;18(2): 128-131. doi: https://doi.org/10.3339/jkspn.2014.18.2.128
A Case of “Full-house” Nephropathy in a Nonlupus Patient
Ha Yeong Yoo1, Mikyung Son1, Myung Hyun Cho1, Byung Ok Kwak1, Hye Won Park1, So Dug Lim2, Sochung Chung1, Kyo sun Kim1
1Department of Pediatrics, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
2Department of Pathology, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea
Corresponding Author: Kyo sun Kim ,Tel: +82-2-2030- 7370, Fax: +82-2-2030- 7748, Email: 19890009@kuh.ac.kr
Received: September 26, 2014;  Accepted: October 14, 2014.
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ABSTRACT
Histopathologic evidence of “full-house” immune complex deposits is a pathognomonic feature of lupus nephritis. This report presents the case of a 12-year-old boy with persistent microscopic hematuria and proteinuria. He was diagnosed with “full-house” nephropathy based on a renal biopsy. However, there was no other clinical or biological evidence of systemic lupus erythematosus (SLE). Although the potential for isolated “full-house” nephropathy preceding SLE is unclear, such patients should be followed for clinical signs and autoantibodies of SLE. In most cases, microscopic hematuria has a good prognosis, and followup usually requires only regular urinalysis. However, we should be aware of isolated “full-house” nephropathy that remains asymptomatic for a long time, as few patients with no clinical signs and negative serology ultimately develop SLE.
Key words: Lupus nephritis | Immunofluorescence | Systemic lupus erythematosus | Biopsy
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