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Journal of the Korean Society of Pediatric Nephrology 2009;13(2): 235-241. doi: https://doi.org/10.3339/jkspn.2009.13.2.235
급성 위장염 환아에서 bicarbonate gap의 임상적 의의
박규희, 정성관, 임형은, 유기환, 홍영숙, 이주원
1고려대학교 의과대학 소아과학교실
2고려대학교 의과대학 소아과학교실
3고려대학교 의과대학 소아과학교실
4고려대학교 의과대학 소아과학교실
5고려대학교 의과대학 소아과학교실
6고려대학교 의과대학 소아과학교실
Clinical Significance of Bicarbonate Gap in Pediatric Patients with Acute Gastroenteritis
Kyu-Hee Park, Seong-Kwan Jung, Hyung-Eun Yim, Kee-Hwan Yoo, Young-Sook Hong, Joo-Won Lee
1Department of Pediatrics, College of Medicine
2Department of Pediatrics, College of Medicine
3Department of Pediatrics, College of Medicine
4Department of Pediatrics, College of Medicine
5Department of Pediatrics, College of Medicine
6Department of Pediatrics, College of Medicine
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ABSTRACT
Purpose : The purpose of this study was to determine the clinical value of bicarbonate gap (BG) in acute gastroenteritis by comparison of clinical manifestations and laboratory findings.
Methods : We retrospectively analyzed 135 patients who had acute gastroenteritis. We classified them into two groups: $BG{leq}-5$ (group A), BG>-5 (group B). We made a comparative study for clinical manifestations, serum electrolyte, albumin, protein, blood urea nitrogen (BUN), creatinine, anion gap (AG), delta anion gap (${Delta}AG$) and delta bicarbonate (${Delta}HCO_3{^-}$) between the two groups.
Results : The duration of hospitalization and diarrhea was significantly longer in group A than group B. In laboratory findings, serum sodium, serum total $CO_2$, total protein, $AG_{corrected}$ and ${Delta}AG$ were lower in group A than group B. ${Delta}HCO_3{^-}$ and chloride were higher in group A than group B.
Conclusion : BG may be a sensitive predictor enough to access the severity of acute gastroenteritis.
Key words: Acute gastroenteritis | Metabolic acidosis | Delta anion gap | Delta bicarbonate
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