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Journal of the Korean Society of Pediatric Nephrology 2006;10(1): 40-44.
소아에서 출혈성 수포를 동반한 $Henoch-Sch{""{o}}nlein$ 자반병 1례
오연미, 정미림, 최혜정, 차희정, 정진영
1울산대학교 의과대학 울산대학교병원 소아과
2울산대학교 의과대학 울산대학교병원 소아과
3울산대학교 의과대학 울산대학교병원 병리과
4울산대학교 의과대학 울산대학교병원 병리과
5울산대학교 의과대학 울산대학교병원 소아과
A Case of $Henoch-Sch{""{o}}nlein$ Purpura with Hemorrhagic Bullae in a Child
Yeon-Mi Oh, Mi-Rim Jung, Hye-Jeong Choi, Hee-Jeong Cha, Jin-Young Jeong
1Department of Pediatrics, Ulsan University College of Medicine
2Department of Pediatrics, Ulsan University College of Medicine
3Department of Pathology, Ulsan University College of Medicine
4Department of Pathology, Ulsan University College of Medicine
5Department of Pediatrics, Ulsan University College of Medicine
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ABSTRACT
[ $Henoch-Sch{""{o}}nlein$ ] purpura(HSP) is a systemic small vessel vasculitis characterized by cutaneous purpura, arthritis, abdominal pain and nephritis. The characteristic rash of HSP consists of palpable purpura on the buttocks and lower extremities. Bullous lesions often appear in adults with HSP, whereas they are very rare in children with HSP. In this case report, the patient presented with arthralgia and abdominal pain and had hemorrhagic bullae as a prominent manifestation of the disease. The skin biopsy of the patient revealed typical leukocytoclastic vasculitis of dermal vessels and prominent IgA and fibrinogen deposits on capillary walls by direct immunofluorescence. We confirmed the diagnosis of HSP and observed improvement of clinical symptoms and signs within a few days after corticosteroid treatment. We therefore report a case with a review of the literature.
Key words: $Henoch-Sch{\""{o}}nlein$ purpura | Hemorrhagic bullae | Leukocytoclastic vasculitis | IgA | Fibrinogen
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