| Home | E-Submission | Sitemap | Contact Us |  
Journal of the Korean Society of Pediatric Nephrology 2005;9(1): 38-45.
소아에서 시행한 치료적 혈장교환술 9례의 임상적 고찰
이지현, 전가원, 박성은, 진동규, 백경훈
1성균관대학교 의과대학 소아과학교실
2성균관대학교 의과대학 소아과학교실
3성균관대학교 의과대학 소아과학교실
4성균관대학교 의과대학 소아과학교실
5성균관대학교 의과대학 소아과학교실
An Experience of Therapeutic Plasma Exchange in 9 Pediatric Patients
Jee-Hyun Lee, Ga-Won Jeon, Sung-Eun Park, Dong-Kyu Jin, Kyung-Hoon Paik
1Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine
2Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine
3Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine
4Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine
5Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine
Share :  
ABSTRACT
Purpose : The purpose of this study was to analyze the therapeutic effect of plasmapheresis in various pediatric diseases.
Methods : Therapeutic plasmapheresis was performed by COBE Spectra centrifugation. Nine cases were included in this study. The number an[;. method of plasmapheresis, together with the progress and prognosis of each case were retrospectively reviewed.
Results : The patients' ages ranged from 26 mont]Is to 16 years of age, and the mean age was 9.9 years. There were S males and 4 females. The underlying diseases requiring plasmapheresis included 2 cases of hemolytic uremic svndrome(HUS), 1 case of lupus nephritis, 2 cases of rapidly Progressive glomerulonephritis(RPGN), 1 case of focal segmental glomorulosclerosis(FSGS), 1 case of systemic vasculitis after pulmonary hemorrhage, 1 case of acute renal failure associated with pulmonary hemoIThage, and 1 case of acute rejection after renal transplantation. The average number of plasmapheresis performed was 6.2 times with a range of 3 to 13 times. The patients with HUS, lupus nephritis, ANCA positive systemic vasculitis induced by pulmonary hemorrhage and ARF-associated pulmonary hemorrhage showed a good response to therapeutic plasmapheresis, but the patients with RPGN, refractory FSGS, and acute rejection after renal transplantation were not responsive to treatment. The most common side effect was hypocalcemia which was rarely symptomatic. Vital signs were not compromised.
Conclusion : Although it is presumptuous to generalize the therapeutic effects of plasma pheresis in different diseases due to the small number of study subjects, this study shows that plasmapheresis may be an effective therapeutic modality in various pediatrics diseases and should be considered as a therapeutic option.
Key words: Plasmapheresis | Renal failure | Children
Editorial Office
124 Bukbyunjeung-ro, Kimpo, Jesewoong 2-103, Gyeonggi-do 10098, Republic of Korea
TEL : +82-31-987-5963   FAX : +82-31-987-5967   E-mail : chikd.editor@gmail.com or ckdeditor@kspn.org

Copyright© Korean Society of Pediatric Nephrology. All rights reserved.                powerd by m2community
About |  Browse Articles |  Current Issue |  For Authors and Reviewers