Characteristics and Recurrence Risk Factors of Urinary Tract Infection in Early Infancy

Kang, Hee-Gyung; Kim, Nam-Hee; Kang, Ju-Hyung; Ha, Il-Soo; Cheong, Hae-Il; Choi, Yong

J Korean Soc Pediatr Nephrol > Volume 8(2); 2004 > Article

J Korean Soc Pediatr Nephrol 2004;8(2): 223-228.

6개월 미만 영아 요로 감염의 특성과 재발의 위험 인자

강희경, 김남희, 강주형, 하일수, 정해일, 최용

¹서울대학교 의과대학 소아과학교실
²서울대학교 의과대학 소아과학교실
³서울대학교 의과대학 소아과학교실
⁴서울대학교 의과대학 소아과학교실
⁵서울대학교 의과대학 소아과학교실
⁶서울대학교 의과대학 소아과학교실

Characteristics and Recurrence Risk Factors of Urinary Tract Infection in Early Infancy

Hee-Gyung Kang, Nam-Hee Kim, Ju-Hyung Kang, Il-Soo Ha, Hae-Il Cheong, Yong Choi

¹Department of Pediatrics, Seoul National University Medical School
²Department of Pediatrics, Seoul National University Medical School
³Department of Pediatrics, Seoul National University Medical School
⁴Department of Pediatrics, Seoul National University Medical School
⁵Department of Pediatrics, Seoul National University Medical School
⁶Department of Pediatrics, Seoul National University Medical School

ABSTRACT

Purpose and
Methods: Urinary tract infection(UTI) is one of the most important diseases of childhood, especially for young infants. To characterize the patients diagnosed with febrile UTI in their first 6 months of life and to explore the risk factors of recurrent UTI, a retrospective study was performed.
Results : Among the 90 patients studied, 77 were boys(86%). First episodes of UTI were diagnosed at the age of $2.5{pm}1.4$ months. These patients underwent ultrasonographic evaluation of urinary tract(n=90) and voiding cystourethrography(n=81) where 53 and 35 studies showed abnormal findings respectively, and a total of 45 cases of urinary tract anomaly including vesicoureteral reflux(VUR, n=35) were diagnosed. Normal findings on ultrasonography indicated decreased risk of VUR in boys of 1-3 months of age(n=30). 53 patients were followed up more than 6 months and 45 episodes of subsequent UTI developed in 29 patients during the first 6-month period. Patients with relapse were older than patients without relapse at the diagnosis of first UTI, but other clinical parameters including abnormal findings on the imaging studies and prophylactic antibiotics prescription were not different between the two groups.
Conclusion : UTI in early infancy occurred mainly in male infants and half of the patients had structural anomalies. USG was of clinical value in detecting anomalies requiring surgical intervention, and to rule out high grade VUR in 1-3 months old boys. Results of the imaging study or prophylactic antibiotics could not modify the risk of recurrent UTI.

Key words: Urinary tract infection | Early infancy | Prophylactic antibiotics