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Journal of the Korean Society of Pediatric Nephrology 2004;8(1): 91-95.
신우요관이행부폐색과 동반된 일과성 가성저알도스테론혈증 1례
최준기, 한혜원, 유한욱, 박영서
1울산대학교 의과대학 서울아산병원 소아과
2울산대학교 의과대학 서울아산병원 소아과
3울산대학교 의과대학 서울아산병원 소아과
4울산대학교 의과대학 서울아산병원 소아과
A Case of Transient Pseudohypoaldosteronism Secondary to Ureteropelvic Junction Obstruction
Jun-Gi Choi, Hye-Won Hahn, Han-Wook You, Young-Seo Park
1Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
2Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
3Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
4Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center
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ABSTRACT
We report a 2-month-old boy who presented with severe hyponatremia and hyperkalemia secondary to ureteropelvic junction(VPJ) obstruction. By prenatal ultrasonography at 19 weeks of gestation, severe hydronephrosis was found which was confirmed postnatally Pyeloplasty was done on the 45th day of life, and fifteen days after pyeloplasty, non-bilious vomiting, decreased activity and dehydration developed. Severe hyponatremia and hyperkalemia were observed, as a result of elevated serum aldosterone and plasma renin activity. The anterior posterior pelvic diameter(APPD) and Society for Fetal Urology(SFU) grade measured showed no interval change before and after pyeloplasty. Pseudohypoaldosteronism was diagnosed, and 2M NaCl was administrated orally for 7 days. The electrolyte imbalance was corrected, and 8 weeks later, the elevated levels of aldosterone and plasma renin activity were normalized. The left hydronephrosis was improved at 5 months of age. We hereby report a transient pseudohypoaldosteronism secondary to UPJ obstruction with a review of the literature.
Key words: Transient pseudohypoaldosteronism | Ureteropelvic junction obstruction
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