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Journal of the Korean Society of Pediatric Nephrology 2003;7(1): 96-102.
메틸말로닌산혈증에 의한 신생아 고암모니아혈증에서 지속적 정정맥 투석 여과법 시행 1례
장원경, 한혜원, 신영림, 박현경, 김애란, 유한욱, 박영서
1울산대학교 의과대학 서울아산병원 소아과
2울산대학교 의과대학 서울아산병원 소아과
3울산대학교 의과대학 서울아산병원 소아과
4울산대학교 의과대학 서울아산병원 소아과
5울산대학교 의과대학 서울아산병원 소아과
6울산대학교 의과대학 서울아산병원 소아과
7울산대학교 의과대학 서울아산병원 소아과
A Case of Continuous Venovenous Hemodiafiltration in the Treatment of Neonatal Hyperammonemia Due to Methylmalonic Acidemia
Won-Kyoung Jhang, Hye-Won Hahn, Young-Lim Shin, Hyun-Kyung Park, Ai-Rhan Kim, Han-Wook Yoo, Young-Seo Park
1Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
2Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
3Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
4Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
5Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
6Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
7Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine
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ABSTRACT
Acute hyperammonemia is a medical emergency in the newborn. Efficient, prompt removal of serum ammonia is essential in preventing irreversible brain damage in order to prevent the profound central nervous system dysfunction due to hyperammonia. We report a case of 2.3 kg, 5-day old girl with methylmalonic acidemia who presented with severe hyperammonemia and was successfully treated with continuous venovenous hemodiafiltration(CVVHDF). CVVHDF is an effective and safe method of ammonia removal in the newborn.
Key words: Continuous venovenous hemodiafiltration | Hyperammonemia | Neonate | Methylmalonic acidemia
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