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Journal of the Korean Society of Pediatric Nephrology 2002;6(1): 102-108.
Escherichia coli O114에 의한 용혈성 요독 증후군 2례
류수정, 한혜원, 유수진, 이병선, 이재규, 김미나, 김의종, 박영서
1울산대학교 의과대학 서울아산병원 소아과
2울산대학교 의과대학 서울아산병원 소아과
3울산대학교 의과대학 서울아산병원 임상병리학과
4울산대학교 의과대학 서울아산병원 소아과
5서울대학교 의과대학 임상병리학과
6울산대학교 의과대학 서울아산병원 임상병리학과
7서울대학교 의과대학 임상병리학과
8울산대학교 의과대학 서울아산병원 소아과
Two cases of Hemolytic Uremic Syndrome Associated with Esecherichia coli O114
Su-Jeung Ryu, Hyewon Hahn, Soo Jin Yoo, Byung-Sun Lee, Jae Kyoo Lee, Mi-Na Kim, Eui Chong Kim, Young Seo Park
1Department of Pediatrics, Asan Medical Center, University of Ulsan, College of Medicine
2Department of Pediatrics, Asan Medical Center, University of Ulsan, College of Medicine
3Department of Clinical Pathology, Asan Medical Center, University of Ulsan, College of Medicine
4Department of Pediatrics, Asan Medical Center, University of Ulsan, College of Medicine
5Seoul National University College of Medicine, Department of Clinical Pathology
6Department of Clinical Pathology, Asan Medical Center, University of Ulsan, College of Medicine
7Seoul National University College of Medicine, Department of Clinical Pathology
8Department of Pediatrics, Asan Medical Center, University of Ulsan, College of Medicine
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ABSTRACT
We report two cases of hemolytic uremic syndrome (HUS) associated with Escherichia coli O114. Two cases were similar and showed the same clinical courses. After prodrome of diarrhea and vomiting lasting 1-2 days, azotemia persisted for about 10 days, and during that period, the patients were on peritoneal dialysis. They recovered without any sequelae after about 15 days. Direct multiplex PCR of stool culture revealed eae and stx2 gene and the result of ELISA done on the colony positive of one gene confirmed Escherichia coli O114. This is the first report of HUS associated with Escherichia coli O114. We recommend, Shiga toxin producing bacterial Infection must be considered and efforts should be made to scrutinize the organism in all diarrhea-prodrome HUS patients.(J Korean Soc Pediatr Nephrol 2002 ;6 : 102-8)
Key words: Hemolytic Uremic Syndrome | Shiga toxin | Escherichia coli O114
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