| Home | E-Submission | Sitemap | Contact Us |  
Journal of the Korean Society of Pediatric Nephrology 2001;5(2): 196-205.
무증상의 고립성 현미경적 혈뇨만을 나타낸 막성 사구체병증
김세희, 노현경, 이영목, 김지홍, 김병길, 홍순원, 정현주
1연세대학교 의과대학 소아과학교실, 신장질환연구소
2연세대학교 의과대학 소아과학교실, 신장질환연구소
3연세대학교 의과대학 소아과학교실, 신장질환연구소
4연세대학교 의과대학 소아과학교실, 신장질환연구소
5연세대학교 의과대학 소아과학교실, 신장질환연구소
6연세대학교 의과대학 병리학교실, 신장질환연구소
7연세대학교 의과대학 병리학교실, 신장질환연구소
Membranous Glomerulopathy Showing Asymptomatic Isolated Microscopic Hematuria Only
Se Heui Kim, Hyun Kyung Roh, Young-Mock Lee, Ji Hong Kim, Pyung-Kil Kim, Soon Won Hong, Hyun Joo Jeong
1Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
2Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
3Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
4Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
5Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University, College of Medicine
6Departments of Pathology, The Institute of Kidney Disease, Yonsei University, College of Medicine
7Departments of Pathology, The Institute of Kidney Disease, Yonsei University, College of Medicine
Share :  
ABSTRACT
Purpose : Membranous glomerulopathy is a glomerular disease characterized by the presence of subepithelial immune deposits with thickening of the capillary wall of the glomerulus without inflammatory change. The pathogenesis of membranous glomerulopathy is still unknown. Its incidence is higher in males, and it is rarely found in infants and adolescents. Among the clinical manifestations proteinuria is most common, while edema and hematuria are present. According to reports from other countries, among few patients diagnosed with membranous glomerulopathy by renal biopsy, show isolated microscopic hematuria without the clinical manifestations. Little research in this area has been performed in Korea, and so we conducted retrograde studies on membranous glomerulopathy associated with isolated microscopic hematuria.
Materials and Methods : We analyzed retrogradely 109 cases of asymptomatic isolated microscopic hematuria that were diagnosed as membranous glomerulopathy by renal biopsy at Yonsei University Severance hospital from January, 1992 to July, 2001.
Results : In 87 of the 109 cases patients were over 15 years old while in 22 cases patients were under 15 at the time of dignosis. Only three patients showed isolated microscopic hematuria without the clinical manifestations and abnormal laboratory findings and they were all male patients under 15 years old.
Conclusion : Few cases of the membranous glomerulopathy show only asymptomatic isolated microscopic hematuria However, since membranous glomerulopathy can be found in patients who present with asymptomatic isolated microscopic hematuria only, if adequate indication for renal biopsy is present, we conclude that renal biopsy must be aggresively pursued in order to find the underlying disease. (J Korean Soc Pediatr Nephrol 2001 ; 5 : 196-205)
Key words: Membranous glomerulopathy asymptomatic isolated microscopic hematuria
TOOLS
PDF Links  PDF Links
Full text via DOI  Full text via DOI
Download Citation  Download Citation
Supplement  Supplement
  E-Mail
Share:      
METRICS
1,054
View
0
Download
Editorial Office
124 Bukbyunjeung-ro, Kimpo, Jesewoong 2-103, Gyeonggi-do 10098, Republic of Korea
TEL : +82-31-987-5963   FAX : +82-31-987-5967   E-mail : chikd.editor@gmail.com or ckdeditor@kspn.org

Copyright© Korean Society of Pediatric Nephrology. All rights reserved.                powerd by m2community
About |  Browse Articles |  Current Issue |  For Authors and Reviewers