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Journal of the Korean Society of Pediatric Nephrology 2001;5(2): 188-195.
막성증식성 사구체신염 제 II형 (Dense Deposit Disease, DDD) 1례
권해식, 오승진, 이영목, 김지홍, 김병길, 강혜윤, 정현주, 최인준
1연세대학교 의과대학 소아과학교실
2연세대학교 의과대학 소아과학교실
3연세대학교 의과대학 소아과학교실
4연세대학교 의과대학 소아과학교실
5연세대학교 의과대학 소아과학교실
6연세대학교 의과대학 병리학교실
7연세대학교 의과대학 병리학교실
8연세대학교 의과대학 병리학교실
A Case of Membranoproliferative Glomerulonephritis Type II (Dense Deposit Disease, DDD)
Hae Sik Kwon, Seung-Jin Oh, Young-Mock Lee, Ji Hong Kim, Pyung-Kil Kim, Hae Youn Kang, Hyeon Joo Jeong, In Joon Choi
1Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
2Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
3Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
4Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
5Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
6Departments of Pediatrics, The Institute of Kidney Disease, Yonsei University College of Medicine
7Departments of Pathology, The Institute of Kidney Disease, Yonsei University College of Medicine
8Departments of Pathology, The Institute of Kidney Disease, Yonsei University College of Medicine
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ABSTRACT
Type II membranoproliferative glomerulonephritis (Dense deposit disease) is an acquired primary glomerular disease characterized by electron microscopic evidence of a continuous dense membrane deposition replacing the lamina densa. It is a subtype of idiopathic membra- noproliferative glomerulonephritis, and was described as a separate entity by Berger and Galle in 1963. It frequently occurs in older chilren and young adults and the clinical course is variable, but is generally progressive. The presenting feature is nephrotic syndrome in many patients, and proteinuria and hematuria are also seen frequently. The purpose of this paper is to present a case of DDD (Dense deposit disease) from a 10 year old boy who was diagnosed as a acute poststreptococcal glomurulonephritis with protenuria, hematuria, and facial edema by renal biopsy 4 years ago. (J, Korean Soc Pediatr Nephrol 2001 ; 5 : 188-95)
Key words: Acquired primary glomerular disease | Dense deposit disease | Memmbranoproliferative glomerulonephritis | Proteinuria | Hematuria | Acute poststreptococcal glomerulonephritis.
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