A Case of Atypical Hemolytic Uremic Syndrome Associated with Invasive Streptococcus pneumoniae Infection

Hwang, Soo-Ja; You, Eun-Sun; Lee, Seung-Joo

J Korean Soc Pediatr Nephrol > Volume 3(1); 1999 > Article

J Korean Soc Pediatr Nephrol 1999;3(1): 104-108.

침윤성 Streptococcus pneumoniae 감염에 의한 비전형적 용혈성 요독 증후군 1 례

황수자, 유은선, 이승주

¹이화여자대학교 의과대학 소아과학교실
²이화여자대학교 의과대학 소아과학교실
³이화여자대학교 의과대학 소아과학교실

A Case of Atypical Hemolytic Uremic Syndrome Associated with Invasive Streptococcus pneumoniae Infection

Soo-Ja Hwang, Eun-Sun You, Seung-Joo Lee

¹Department of Pediatrics, Ewha Womans University, College of Medicine
²Department of Pediatrics, Ewha Womans University, College of Medicine
³Department of Pediatrics, Ewha Womans University, College of Medicine

ABSTRACT

Atypical hemolytic uremic syndrome associated with neuraminidase-producing Streptococcus pneumoniae usually associated with invasive infection such as fulminant pneumonia, sepsis, and meningitis and may occur earlier in lift and has a higher mortality rate than typical hemolytic uremic syndrome. We have experienced a 22-month-old female patient with hemolytic uremic syndrome associated with S. pneumoniae pneumonia and empyema. The patient was treated with ceftriaxone and washed red blood cell transfusion. As the disese course could be aggravated by the use of blood products containing anti-Tomsen-Friedenreich antigen, early recognition and sensible use of blood products such as washed RBC might lead to the improved outcome.

Key words: S. pneumoniae pneumonia and empyema | Atypical hemolytic uremic syndrome | Anti-Tomsen-Friedenreich antigen | Washed RBC